Profhilo is one of the best-known lines of dermal fillers, and it is commonly used in the cosmetology and aesthetics industry.
In this article, we will answer the question of what is Profhilo, the variants, and the alternatives to it.
What is Profhilo?
Profhilo is an injectable treatment designed to combat skin aging by stimulating the natural production of collagen and elastin.
Unlike traditional dermal fillers, whose main ingredient is Hyaluronic Acid, Profhilo is composed also of poly-L-lactic acid, which promotes collagen formation.
Profhilo is known for its action of bio-remodeling the skin.
It contains one of the highest concentrations of hyaluronic acid available, which is gradually released to stimulate the production of collagen and elastin.
An increased production of collagen and elastin results in improved skin tone, texture, hydration, and overall radiance.
Profhilo is very effective in its ability to spread evenly across the skin, providing a natural and youthful look, along with a subtle restructuring of the skin without altering facial expressions.
Who is the manufacturer of Profhilo?
Profhilo is developed and manufactured by IBSA Institut Biochimique SA, a renowned Swiss pharmaceutical company.
IBSA was founded a long time ago (in 1945) and is also the producer of the line of products Aliaxin and Viscoderm.
In our catalog, we have a category specifically dedicated to IBSA, but at the time of writing this post, the only line of products you can find on our site from IBSA is Profhilo.

IBSA Derma (based in Lugano, Switzerland) is the manufacturer from Profhilo
What is poly-L-lactic acid, the main ingredient of Profhilo?
Poly-L-lactic acid (known for its acronym PLLA) is a biocompatible and biodegradable synthetic polymer that has been used in medical applications for decades.
It is known for its ability to stimulate collagen production when injected into the skin.
PLLA works by triggering the body’s natural regenerative processes, leading to gradual and natural-looking improvements in skin thickness and elasticity.
Over time, PLLA particles are broken down by the body, leaving behind newly formed collagen that provides long-lasting results.
If you want to check what other components are also common within dermal fillers aside from PLLA, check our article what are dermal fillers made of.
What is Profhilo used for and where?
Profhilo is primarily used to counteract the effects of aging by restoring collagen levels in the skin.
The main areas of action of Profhilo are:
- Face
- Neck
- Décolletage
- Hands
- Inner arm
By stimulating collagen and elastin synthesis in those areas, Profhilo helps to improve skin firmness and elasticity.
Patients often notice a significant improvement in skin hydration, texture, and overall appearance after treatment.
What variants of Profhilo are available in the market?

Profhilo Body Kit appeared as a combined solution with injectable HA, patches and cream for larger body areas
Profhilo offers a few product variants tailored to address specific aesthetic concerns and treatment areas.
Profhilo 1x2ml
Profhilo 1 x 2 ml is the standard Profhilo formulation, containing 2ml solution with 3,2% – 32mg of hyaluronic acid concentration.
Profhilo Structura
Profhilo Structura is designed for areas requiring more structural support and volume restoration, so the 2ml solution has a concentration of 4,5% – 45mg of hyaluronic acid.
It is ideal for treating deeper lines and wrinkles, as well as areas with significant skin laxity. The formulation provides a lifting effect while enhancing skin firmness.
Profhilo Body Kit
The Profhilo Body Kit is specifically formulated for body treatments, targeting areas such as the abdomen, arms, and thighs.
This kit combines the hyaluronic acid from Profhilo with:
- Body patches with natural components like Salvia Haenkei, Arnica Montana, and Pineapple extract.
- Low & High molecular weight hyaluronic acid cream.
Profhilo Body Kit aims to improve skin laxity and hydration in larger surface areas with the combination of injectable HA, patches, and HA cream.
Alternatives to Profhilo
While Profhilo is a leading treatment for collagen induction, there are also other options available for professionals seeking to offer the best in their clinics and consultations.
Alternative collagen inducers that you can find in our portfolio include:
- Sculptra: An injectable treatment containing poly-L-lactic acid that stimulates collagen production to restore facial volume and reduce wrinkles.
- Radiesse: A dermal filler composed of calcium hydroxylapatite microspheres that provides immediate volume and stimulates collagen production.
Each of these treatments has its own set of indications, benefits, and considerations and the application should be . Consultation with a qualified medical professional is essential to determine the most appropriate option based on individual needs and goals.
Disclaimer
This content is intended for aesthetic professionals only. The information provided is for informational purposes and should not be used as a substitute for professional medical advice, diagnosis, or treatment.
If you are an individual looking for aesthetic information, please seek the guidance of a qualified clinic/professional/consultant with any questions regarding treatment options.
If you are a professional in the industry, TopDermal can be your B2B partner for dermal fillers, mesotherapy products, or materials like cannulas, needles, and COG PDOs: we have extensive experience in the dermal filler industry and we can ship anywhere in Europe in a matter of days.
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