Collagen is a crucial protein responsible for maintaining the firmness, elasticity, and youthful appearance of our skin. As we age, collagen production naturally declines, leading to wrinkles, sagging, and loss of volume. Fortunately, aesthetic medicine offers a range of solutions to restore and stimulate collagen levels, with one of the most effective being collagen fillers and collagen boosters.
To understand collagen better, including its definition, uses, and natural sources, check out our detailed article from 2020 on what is the collagen protein.
Additionally, you can explore our article on neo-collagenesis to learn how the body produces collagen and how you can naturally boost this effect.
The best collagen fillers for stimulating collagen production
Dermal fillers designed to stimulate collagen production offer gradual, long-lasting improvements in skin quality and facial volume by replenishing the collagen in the skin.
Below, we introduce the top products available on TopDermal that not only restore lost volume but also encourage your skin to produce its own collagen for sustained rejuvenation.
Aquashine

Range of Aquashine products
Aquashine is a biorevitalizant product combining hyaluronic acid with a powerful peptide complex and multivitamins. It hydrates the skin, improves elasticity, and stimulates natural collagen production, making it ideal for anti-aging treatments and skin rejuvenation procedures.
Sculptra

Sculptra is a unique collagen replenishing treatment designed to restore lost collagen and volume in the face
Sculptra is a well-known injectable filler containing poly-L-lactic acid (PLLA), a biostimulatory agent that gradually stimulates collagen synthesis.
It works deep within the dermis to restore facial volume and smooth out wrinkles over a series of treatments, delivering natural-looking, long-lasting results. If you want to compare Sculptra with another big competitor, we have another article comparing Sculptra vs Radiesse.
Gouri
Gouri is a fully liquid injectable form of polycaprolactone (PCL) that distributes evenly within the skin to induce collagenesis. Known for its ability to improve skin density, firmness, and texture, Gouri offers gradual, holistic rejuvenation effects without changing facial contours dramatically.
Aesplla
Aesplla is another PLLA-based filler designed for deep dermal injections. It stimulates the body’s natural collagen production process, improving skin thickness and elasticity. Ideal for restoring volume in the mid-face, temples, and chin, Aesplla provides progressive and long-lasting enhancements.
Karisma Rh Collagen
Karisma Rh Collagen is a unique dermal filler formulated with recombinant human collagen, hyaluronic acid, and carboxymethylcellulose.
It offers immediate volumizing effects while promoting the skin’s own collagen regeneration, resulting in natural, youthful-looking skin with improved structure and elasticity.
Collagen fillers found in out catalaog: a price comparison table
In the table below you will find a list of all the collagen fillers mentioned above, with their price and a direct link to the product in our catalog:
Filler Name | Main Ingredient/Composition | Price |
---|---|---|
Aquashine | Hyaluronic Acid, Peptides, Multivitamins | 79,95€ |
Sculptra | Poly-L-lactic Acid (PLLA) | 344,95€ |
Gouri | Polycaprolactone (PCL) | 84,95€ |
Aesplla | Poly-L-lactic Acid (PLLA) | 129,95€ |
Karisma Rh Collagen | Recombinant Human Collagen, Hyaluronic Acid | 99,95€ |
Note: prices may have changed by the time you read this article.
Important: this information is for professionals only
Please note that the information provided in this article is intended strictly for professional use. TopDermal.com exclusively supplies dermal fillers and medical aesthetic products to certified cosmetologists, dermatologists, and licensed clinics.
If you are an end-user, we strongly advise you to consult a professional aesthetic specialist for personalized advice and treatment options. Do not self-diagnose which dermatological issue you experience and which product you need, let a qualified professional take care of it.
If you are a licensed practitioner, we invite you to collaborate with TopDermal. Register with us today and receive a 5% discount on your first purchase, along with discounts for bulk purchases and more. Check our loyalty program page for more information about all our promotions.
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